These UV sterilisation cabinets provide a convenient area for setting up PCR reactions in a nucleic acid free environment thus limiting PCR reaction contamination. Acting effectively as a low cost alternative to a Cleanroom, the powerful UV lights on the cabinets denature nucleic acids in 5 to 30 minutes making them unsuitable for amplification. The cabinet incorporates safety features to prevent user exposure to UV light. The UV lights themselves are timer controlled and there are safety switches on the cabinets doors which turn off the UV lights when opened. Constructed from 10 mm acrylic, the cabinets also act as efficient shields from beta radiation emissions and can therefore be safely used with isotopes such as ³²P.